| Edit | RomName | Publisher | Year | Country | PlatForm | Cheat | GenMSX |
 | R-Type | IREM | 1988 |  |  | |  |
| R-Type Enhancement Patch (ROM add-on) | BiFi Productions | 2010 |  |  | | |
| RSC Ensemblador | Manhattan Transfer | 19xx |  | | | |
| RX Editor YRM-302 | YAMAHA | 1986 | | | | |
| Raid On Bungeling Bay | Brøderbund Software | 1984 |  | | | |
| Rainbow Stories | Al Alamiah | 1986 |  | | | |
| Rally-X | NAMCO | 1984 | | | | |
| Rambo | Pack-In-Video | 1985 | | | | |
| Rapid Burst | Karoshi Corporation | 2004 | | | | |
| Rastan Saga | TAITO | 1988 | | | | |
| RatBox | AG Software | 2010 |  | | | |
| Real Tennis | Takara | 1983 | | | | |
| Real Time Sequencer DMS-01 | Digital Music Systems | 1985 |  | | | |
| Red Alert ! | WYZ | 2008 | | | | |
| Red Zone | Yellow Horn | 1985 | | | | |
| Relics - MSX1 Version | Bothtec | 1986 | | | | |
| Relics - MSX2 Version | Bothtec | 1986 | | | | |
| Renju & Ojama Dogs | Pony Canyon | 1985 | | | | |
| Replicart | Sony | 1987 | | | | |
| Retaliot | Video Hazard | 2009 | | | | |
| Return of Ishtar, The | NAMCO | 1988 | | | | |
| Return of Jelda | Softmen / Carry Lab | 1987 |  | | | |
| Revenge Of The Boing Ball | R.Bittencourt | 2004 |  | | | |
| Reversi | Daniel Bienvenu | 2003 | |  | | |
| Reversi Demo | Daniel Bienvenu | 2001 | | | | |
| Rice | Konami | 1989 | | | | |
| Rice 2 | Konami | 1989 | | | | |
| Rick & Mick's Adventure | Humming Bird Soft | 1987 | | | | |
| Rise Out From Dungeons | ASCII | 1983 | | | | |
| River | Darkstone | 2008 | | | | |
| River Raid | Activision | 1984 | | | | |
| River Raid | Activision | 1984 | | | | |
| Road Fighter | Konami | 1985 | | | | |
| Robin Hood | Xonox | 1984 | | | | |
| Robofrog | Mass Tael | 1985 |  | | | |
| Robots | German Gomez Herrera | 2008 | | | | |
| Robots | Michel d'Alger | 2011 |  | | | |
| Robowres 2001 | Micronet | 1987 | | | | |
| Roc 'N Rope | Konami | 1983 | | | | |
| Roc'N Rope | Coleco | 1984 | | | | |
| Rock 'N Bolt | Telegames | 1984 | | | | |
| Rock'n Roller | Kaeru Soft | 1988 | | | | |
| Rockn' Bolt | Activision | 1985 | | | | |
| Rocky Super Action Boxing | Coleco | 1983 | | | | |
| Roger Rubbish | Spectravideo | 1984 |  | | | |
| Rogo RobotArm SVI-2000 | SVI | 1986 | | | | |
| Roller Ball | HAL Laboratory | 1984 | | | | |
| Rolloverture | Sunrise | 1983 | | | | |
| Root Beer Tapper | Coleco | 1984 | | | | |
| Rotating MSX | WYZ | 2004 | | | | |
| Rotors | ASCII | 1984 | | | | |
| Royal Blood | KOEI | 1991 | | | | |
| Ruin Master | Kai Magazine | 2016 | | | | |
| Running Naked in a field of flowers | Infinite | 2006 | | | | |